Safety and Effectiveness of Eculizumab in Patients With Refractory Ocular or Ocular‐Predominant Myasthenia Gravis: A Case Series
In patients with refractory ocular or ocular-predominant MG, eculizumab had a rapid onset of therapeutic effect that was sustained after 12 weeks, regardless of the antibody titer. The favorable safety profile supports its use in treatment-resistant cases of refractory OMG or ocular-predominant MG. Larger randomized controlled trials are needed to establish the long-term effectiveness and optimize treatment protocols.
Authors
- Qi Niu (ORCID: https://orcid.org/0000-0001-9237-9553)
- Shiyu Shi
- Pan You
- Xi Cheng
- Yu Zhang
- Wenping Yang
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- Muscle & Nerve
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1002/mus.70183
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 0.00