Crosstalk between SPP1 + macrophages and ITGA5 + fibroblasts promotes hepatocellular carcinoma metastasis
We present a dynamic transcriptional profile of immune microenvironment evolution during HCC development, aiding in the refinement of diagnostics and the optimization of therapy strategies.
Authors
- Jianjun Zhu (ORCID: https://orcid.org/0000-0001-5338-7825)
- Jingjia Chang
- Li Niu (ORCID: https://orcid.org/0000-0003-0627-1963)
- Zhigao Ou
- Lei Li (ORCID: https://orcid.org/0000-0001-8723-3461)
- Xintong Zhang (ORCID: https://orcid.org/0000-0003-0561-8902)
- Lu Fan (ORCID: https://orcid.org/0009-0002-1365-0996)
- Tian Yang
- Hao Wu
- Jia Fengfeng
- Ting Tang
- Chen Huiying
- Ni Xiyun
- Yubo Li
- Ming Liu
- Zhao Guoqing
Institutions
- Shanxi Medical University (CN)
- Anhui Medical University (CN)
- Xian Central Hospital (CN)
- Shanxi Coal Transportation and Sales Group (China) (CN)
- Taiyuan Institute of Technology (CN)
- Taiyuan Central Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- China Coal Research Institute (China) (CN)
- Taiyuan University of Science and Technology (CN)
Publication Details
- Journal
- Hepatology Communications
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1097/hc9.0000000000000907
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00