Biological evaluation of novel 6,9-disubstituted purine analogues in high-grade serous ovarian cancer cell lines
Compound <b>8</b> may disrupt key proliferative mechanisms in cancer cells by interfering with DNA synthesis and activating programmed cell death pathways. These findings suggest that compound <b>8</b> is a promising lead candidate for further development in ovarian cancer therapeutics.
Authors
- İrem Durmaz (ORCID: https://orcid.org/0000-0001-5037-7883)
- Duygu Altiparmak
- Meral TUNÇBİLEK
- Deren Demirel Yavuz
- PINAR KUL KARADENİZLİ
Institutions
- Koç University (TR)
- Ankara University (TR)
Publication Details
- Journal
- TURKISH JOURNAL OF BIOLOGY
- Published
- 2026-02-23
- DOI
- https://doi.org/10.55730/1300-0152.2788
- Primary Topic
- Biochemical and Molecular Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi