Clinical Significance of LRG1 Protein Expression in Locally Advanced Gastric Cancer After Curative Resection

High LRG1 protein expression in primary tumor cells is an independent predictor of poor survival in patients with pStage II/III GC after curative resection. Quantitative assessment of tumoral LRG1 may serve as a useful prognostic biomarker for risk stratification in locally advanced GC.

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Publication Details

Journal
Anticancer Research
Published
2026-02-27
DOI
https://doi.org/10.21873/anticanres.18057
Primary Topic
Clusterin in disease pathology
Type
article
Field-Weighted Citation Impact
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article

Clinical Significance of LRG1 Protein Expression in Locally Advanced Gastric Cancer After Curative Resection

ITARU HASHIMOTO, Takanobu Yamada, Norihiro Akimoto, Takashi Oshima et al.
Anticancer Research
Clusterin in disease pathology
article

Clinical Significance of LRG1 Protein Expression in Locally Advanced Gastric Cancer After Curative Resection

ITARU HASHIMOTO, Takanobu Yamada, Norihiro Akimoto, Takashi Oshima, Yukihiko Hiroshima, T. Ogata, YOHEI MIYAGI, TOMOKO JITSUKATA, SHINSUKE NAGASAWA, KYOHEI KANEMATSU, YUTA NAKAYAMA, AYA SAITO, HAYATO WATANABE
article en

Abstract

High LRG1 protein expression in primary tumor cells is an independent predictor of poor survival in patients with pStage II/III GC after curative resection. Quantitative assessment of tumoral LRG1 may serve as a useful prognostic biomarker for risk stratification in locally advanced GC.

Anticancer ResearchVol. 46(3)
Kanagawa Prefectural Hospital Organization (JP), Yokohama City University Hospital (JP), Kanagawa Cancer Center, Yokohama City University (JP)
No poverty
Openalex Percentile: Top 39%
Clusterin in disease pathology
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