Enumeration, Phenotyping, and Clinical Associations of Tissue‐Resident T Cells in the Ecto‐ and Endocervix of Women Attending a Colposcopy Clinic

Our data suggest that T<sub>RM</sub> are more abundant in ecto- versus endocervical samples, which may reflect differences in commonly used sampling methods. Location and heterogeneous expression profiles underscore the need to better understand their role in microbial interactions, inflammation, and genital infection susceptibility in women.

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Publication Details

Journal
American Journal of Reproductive Immunology
Published
2026-02-27
DOI
https://doi.org/10.1111/aji.70222
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
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article

Enumeration, Phenotyping, and Clinical Associations of Tissue‐Resident T Cells in the Ecto‐ and Endocervix of Women Attending a Colposcopy Clinic

Nyambura Kahia, Bonnie Sandberg, Faisal Nuhu, Karen Downing et al.
American Journal of Reproductive Immunology
Reproductive tract infections research
article

Enumeration, Phenotyping, and Clinical Associations of Tissue‐Resident T Cells in the Ecto‐ and Endocervix of Women Attending a Colposcopy Clinic

Nyambura Kahia, Bonnie Sandberg, Faisal Nuhu, Karen Downing, Christine Robinson, Alon Altman, Fran Mulhall, Yoav Keynan, Heather Elands, Vanessa Poliquin, Janilyn Arsenio, Naima Jahan, Lyle R McKinnon, Robyn Groff, Aloysious Ssemaganda, Myo Minn Oo, Dafne Rozenberg
article en

Abstract

Our data suggest that T<sub>RM</sub> are more abundant in ecto- versus endocervical samples, which may reflect differences in commonly used sampling methods. Location and heterogeneous expression profiles underscore the need to better understand their role in microbial interactions, inflammation, and genital infection susceptibility in women.

American Journal of Reproductive ImmunologyVol. 95(3)
University of Nairobi (KE), Centre for the AIDS Programme of Research in South Africa (ZA), Research Manitoba (CA), CancerCare Manitoba (CA), Research Institute in Oncology and Hematology (CA), University of Manitoba (CA)
Gender equality
Openalex Percentile: Top 40%
Reproductive tract infections research
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