HPV18-positive Small Cell Neuroendocrine Carcinoma of the Uterine Cervix Treated With Immunotherapy: A Case Report
Comprehensive multimodal therapy, including standard surgery, neoadjuvant and adjuvant chemotherapy, chemoradiation for recurrent lymph nodes, and immune checkpoint inhibition, can achieve a remarkable response in advanced SCNEC harboring <i>CD274</i> (PD-L1) amplification and HPV18 infection.
Authors
- Toshiyuki Sasagawa (ORCID: https://orcid.org/0000-0002-8480-844X)
- Sakiko Masumoto
- Yuichi Hori (ORCID: https://orcid.org/0000-0001-6281-0998)
- Ken Yamamoto (ORCID: https://orcid.org/0000-0002-1117-2081)
- Toshie Hara
- Jun Kato (ORCID: https://orcid.org/0000-0003-4832-8024)
- Manabu Muto
- Yayoi Ando (ORCID: https://orcid.org/0009-0000-0349-0832)
- Yasuharu Kaizaki
- Masaaki Tanaka
- ATSUSHI YAMADA
Institutions
- Fukui Prefectural Hospital (JP)
- Kanazawa Medical University Hospital (JP)
- National Cancer Center Hospital East (JP)
- Kyoto University Hospital (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2026-02-27
- DOI
- https://doi.org/10.21873/anticanres.18067
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00