Risk of Non-colorectal Malignancies in Sporadic <i>Versus</i> Lynch Syndrome–associated dMMR Colorectal Cancer
Sporadic dMMR CRC confers a substantially lower risk of non-colorectal malignancy than Lynch syndrome-associated CRC. These findings underscore the importance of incorporating MMR etiology into personalized surveillance strategies.
Authors
- Tomáš Svoboda (ORCID: https://orcid.org/0000-0003-2734-4746)
- Richard Palmqvist (ORCID: https://orcid.org/0000-0002-9933-2843)
- Jaana Hagström (ORCID: https://orcid.org/0000-0001-6079-7881)
- Tuomas Kaprio (ORCID: https://orcid.org/0000-0002-0377-9975)
- Camilla Böckelman (ORCID: https://orcid.org/0000-0002-1628-0305)
- Sofia Edin (ORCID: https://orcid.org/0000-0002-1901-8011)
- Pavel Fabián
- Jan Novotný (ORCID: https://orcid.org/0000-0001-6021-0577)
- Ioannis Gkekas (ORCID: https://orcid.org/0009-0006-7840-6344)
- C. Haglund
- KARIN STRIGÅRD
Institutions
- University of Helsinki (FI)
- University of Turku (FI)
- Charles University (CZ)
- Helsinki University Hospital (FI)
- Masaryk Memorial Cancer Institute (CZ)
- Umeå University (SE)
Publication Details
- Journal
- Anticancer Research
- Published
- 2026-02-27
- DOI
- https://doi.org/10.21873/anticanres.18043
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medicinska Understödsföreningen Liv och Hälsa
- Finska Läkaresällskapet
- Sigrid Juséliuksen Säätiö