Integrated Bioinformatics Analysis of a TF-miRNA–mRNA Regulatory Network in Retinal Vein Occlusion with Metabolic Syndrome and its Association with Clinical Predictors

This study proposes a TF-miRNA-mRNA network associated with RVO-MetS comorbidity and offers molecular support for previously reported clinical predictors. ABCA1 and hsa‑miR‑192‑5p may serve as potential biomarkers. The limited sample size warrants cautious interpretation, and these findings provide a hypothesis‑generating foundation for future targeted investigations.

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Publication Details

Journal
Current Eye Research
Published
2026-02-27
DOI
https://doi.org/10.1080/02713683.2026.2631815
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
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article

Integrated Bioinformatics Analysis of a TF-miRNA–mRNA Regulatory Network in Retinal Vein Occlusion with Metabolic Syndrome and its Association with Clinical Predictors

Chunlan Liang, Qi Shi, Guocheng Yu, Yuyao Diao et al.
Current Eye Research
Retinal Imaging and Analysis
article

Integrated Bioinformatics Analysis of a TF-miRNA–mRNA Regulatory Network in Retinal Vein Occlusion with Metabolic Syndrome and its Association with Clinical Predictors

Chunlan Liang, Qi Shi, Guocheng Yu, Yuyao Diao, Jingxiang Zhong, Lian Liu, Shangli Jin, Haixia Xie
article en

Abstract

This study proposes a TF-miRNA-mRNA network associated with RVO-MetS comorbidity and offers molecular support for previously reported clinical predictors. ABCA1 and hsa‑miR‑192‑5p may serve as potential biomarkers. The limited sample size warrants cautious interpretation, and these findings provide a hypothesis‑generating foundation for future targeted investigations.

Current Eye Research
Jinan University (CN), First Affiliated Hospital of Jinan University (CN)
Openalex Percentile: Top 42%
Retinal Imaging and Analysis
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