Exploring the application boundaries of LLMs in mental health: a systematic scoping review

LLMs have emerged as sophisticated "Mental Health Agents" with immense potential for providing personalized, knowledge-guided interventions. The core challenge for future development is to transcend basic functionality and achieve clinical rigor. Future research must prioritize deep specialization into psychological models, enhance multimodal integration for comprehensive patient assessment, and urgently develop robust ethical and cultural adaptation frameworks to ensure the models are safe, globally equitable, and reliable for clinical deployment, thereby fulfilling their potential to alleviate the global mental health resource crisis.

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Publication Details

Journal
Frontiers in Psychology
Published
2026-02-27
DOI
https://doi.org/10.3389/fpsyg.2025.1715306
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring the application boundaries of LLMs in mental health: a systematic scoping review

Patrick Cheong‐Iao Pang, Ting Liu, Qin Yang, Yiming Luo et al.
Frontiers in Psychology
Artificial Intelligence in Healthcare and Education
article

Exploring the application boundaries of LLMs in mental health: a systematic scoping review

Patrick Cheong‐Iao Pang, Ting Liu, Qin Yang, Yiming Luo, Xiang Ao, Jinhua Yang, Tianyue Niu
article en

Abstract

LLMs have emerged as sophisticated "Mental Health Agents" with immense potential for providing personalized, knowledge-guided interventions. The core challenge for future development is to transcend basic functionality and achieve clinical rigor. Future research must prioritize deep specialization into psychological models, enhance multimodal integration for comprehensive patient assessment, and urgently develop robust ethical and cultural adaptation frameworks to ensure the models are safe, globally equitable, and reliable for clinical deployment, thereby fulfilling their potential to alleviate the global mental health resource crisis.

Frontiers in PsychologyVol. 16
Jiangnan University (CN), Tongji University (CN), Georgia Institute of Technology (US), Data Assurance and Communication Security (CN), Macao Polytechnic University (MO)
Fundo para o Desenvolvimento das Ciências e da Tecnologia
Quality Education
Openalex Percentile: Top 42%
Artificial Intelligence in Healthcare and Education
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