Repeated Unstimulated Whole Saliva Collection: A Reliable Approach to Improve Diagnostic Accuracy
Single UWS measurements are influenced by substantial physiological variability, which may lead to diagnostic misclassification. Averaging multiple standardised collections, particularly in the evening, enhances reliability and may optimise diagnostic accuracy. This protocol supports refinement of clinical guidelines and the implementation of home-based saliva testing for salivary gland dysfunction.
Authors
- Maria Eleonora Bizzoca (ORCID: https://orcid.org/0000-0002-6722-6499)
- Nicola Cirillo (ORCID: https://orcid.org/0000-0003-1429-1323)
- Rosa María López-Pintor
- Giuseppe Troiano
- Gennaro Musella
- Lorenzo Lo Muzio
- Vito Carlo Alberto Caponio
- Filippo Sisto
Institutions
- University of Foggia (IT)
- Universidad Complutense de Madrid (ES)
- LUM Jean Monnet University (IT)
- Link Campus University (IT)
Publication Details
- Journal
- Journal of Oral Rehabilitation
- Published
- 2026-02-25
- DOI
- https://doi.org/10.1111/joor.70172
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.00