Genome-wide DNA methylation profiling in COVID-19 positive patients reveals alterations in pathways linked to neurological dysfunction
Our findings underscore the potential importance of epigenetic regulation in the acute responses to SARS-CoV-2 infection and highlight an overlap with epigenetic mechanisms relevant for neuropsychiatric disease processes.
Authors
- Saima Zameer (ORCID: https://orcid.org/0000-0001-9595-9609)
- Juozas Gordevičius (ORCID: https://orcid.org/0000-0003-3190-6721)
- Ieva Kerševičiūtė
- Miglė Gabrielaitė (ORCID: https://orcid.org/0000-0002-7959-8767)
- Sanam Khan (ORCID: https://orcid.org/0000-0001-6072-2273)
- Patrik Brundin (ORCID: https://orcid.org/0000-0003-2924-5186)
- Jennifer A. Steiner (ORCID: https://orcid.org/0000-0003-0953-1310)
- Lena Brundin (ORCID: https://orcid.org/0000-0002-8327-6242)
- Ehraz Anis (ORCID: https://orcid.org/0000-0003-2172-4895)
- Qiong Sha (ORCID: https://orcid.org/0000-0002-8474-9769)
- Milda Milčiūtė (ORCID: https://orcid.org/0009-0002-2214-9140)
- Andrew Pospisilik
- Martha L. Escobar Galvis
- Nazia Saiyed
Institutions
- Roche (Switzerland) (CH)
- Van Andel Institute (US)
- Oakland University (US)
- Royal Oak Community Coalition (US)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2026-02-27
- DOI
- https://doi.org/10.1186/s13148-026-02094-0
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00