Incidence and Characteristics of HBV Reactivation‐Related Events Following HBsAg Seroclearance: Long‐Term Follow‐up of a Population‐Based Cohort in Japan

Reactivation-related events after HBsAg seroclearance were rare in this population-based cohort. These findings suggest that HBsAg seroclearance may not necessarily indicate complete viral eradication and that careful long-term monitoring may be warranted, particularly in patients with advanced liver disease.

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Publication Details

Journal
Hepatology Research
Published
2026-02-26
DOI
https://doi.org/10.1111/hepr.70146
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Incidence and Characteristics of HBV Reactivation‐Related Events Following HBsAg Seroclearance: Long‐Term Follow‐up of a Population‐Based Cohort in Japan

Junko Tanaka, Satoshi Shirahama, Takahiro Yasaka, Kazumi Yamasaki et al.
Hepatology Research
Hepatitis B Virus Studies
article

Incidence and Characteristics of HBV Reactivation‐Related Events Following HBsAg Seroclearance: Long‐Term Follow‐up of a Population‐Based Cohort in Japan

Junko Tanaka, Satoshi Shirahama, Takahiro Yasaka, Kazumi Yamasaki, Hiroaki Okamoto, Hiroshi Yatsuhashi, Shota Yamaguchi, Masashi Mizokami
article en

Abstract

Reactivation-related events after HBsAg seroclearance were rare in this population-based cohort. These findings suggest that HBsAg seroclearance may not necessarily indicate complete viral eradication and that careful long-term monitoring may be warranted, particularly in patients with advanced liver disease.

Hepatology Research
Hiroshima University (JP), Jichi Medical University (JP), Mizushima Central Hospital (JP), Photodigm (United States) (US), Nagasaki Medical Center (JP), National Institute of Advanced Industrial Science and Technology (JP)
Openalex Percentile: Top 41%
Hepatitis B Virus Studies
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