Research trends of mitochondrial dysfunction in hepatic fibrosis: a bibliometric analysis

Based on our previous discussions, mitochondria are increasingly recognized as central to the onset and progression of hepatic fibrosis. Related research is advancing rapidly and has become a key area for interdisciplinary collaboration. Future efforts should focus on: validating mitochondrial function biomarkers such as circulating mtDNA and mitochondria-specific metabolites; refining patient stratification based on mitochondrial dysfunction phenotypes (such as metabolic imbalance type, oxidative stress type); and advancing therapeutic strategies targeting mitochondrial quality control, metabolism, and redox balance. This will translate deep mechanistic insights into effective solutions for improving the clinical management of hepatic fibrosis.