Comparison of weekly docetaxel regimens in prostate cancer: a systematic review and frequentist network meta-analysis

Docetaxel dosing schedules show comparable PSA response rates. Triweekly dosing prolongs time to treatment failure but is associated with greater toxicity, whereas weekly dosing offers better tolerability. Treatment decisions should balance efficacy and safety based on individual patient characteristics.

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Publication Details

Journal
Exploration of Targeted Anti-tumor Therapy
Published
2026-02-27
DOI
https://doi.org/10.37349/etat.2026.1002360
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparison of weekly docetaxel regimens in prostate cancer: a systematic review and frequentist network meta-analysis

Waseef Ullah, Fatima Sajjad, Osama Ahmad, Shree Rath et al.
Exploration of Targeted Anti-tumor Therapy
Prostate Cancer Treatment and Research
article

Comparison of weekly docetaxel regimens in prostate cancer: a systematic review and frequentist network meta-analysis

Waseef Ullah, Fatima Sajjad, Osama Ahmad, Shree Rath, Muzamil Khan, Fareeda, Umama Alam, Ahmad Omar Saleh, Amar Lal, Z A R Y A B Bacha, K Abdul Rehman, Umair Hayat
article en

Abstract

Docetaxel dosing schedules show comparable PSA response rates. Triweekly dosing prolongs time to treatment failure but is associated with greater toxicity, whereas weekly dosing offers better tolerability. Treatment decisions should balance efficacy and safety based on individual patient characteristics.

Exploration of Targeted Anti-tumor TherapyVol. 7
University of Jordan (JO), Khyber Medical College (PK), George Washington University (US), CMH Lahore Medical College and Institute of Dentistry (PK), Lady Reading Hospital (PK), All India Institute of Medical Sciences Bhubaneswar (IN), National University of Medical Sciences (PK), Penn State Milton S. Hershey Medical Center (US)
Good health and well-being
Openalex Percentile: Top 40%
Prostate Cancer Treatment and Research
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