1,5-Anhydroglucitol Aggravates Acute Liver Failure via the PPARα Signaling Pathway
Acute liver failure (ALF) is a severe hepatic injury associated with high short-term mortality. Our previous study found that 1,5-anhydroglucitol (1,5AG) levels correlate with clinical outcomes in patients with liver failure. This study aimed to explore the potential effects and mechanisms of 1,5AG in ALF.
Authors
- Luyang Zhang (ORCID: https://orcid.org/0000-0003-2620-9251)
- Yalei Zhao
- Xiaoxi Ouyang
- Lanjuan Li
- Qiuhong Liu
- Qian Li
- Danhua Zhu
- Yaqi Zhang
- Qingqing Hu
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2026-02-27
- DOI
- https://doi.org/10.14218/jcth.2025.00523
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Zhejiang University
- State Key Laboratory for Diagnosis and Treatment of Infectious Diseases
- State Key Laboratory of Infectious Disease Prevention and Control