Tumour-infiltrating lymphocytes do not predict survival in human papillomavirus-associated oropharyngeal squamous cell carcinoma: a single institution retrospective review

TIL density in HPV+OPSCC has been reported to predict survival outcomes. This is not supported by the findings of this study. Further prospective evaluation with a standardised scoring technique may fully elicit the prognostic value of TILs in HPV+OPSCC.

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Publication Details

Journal
The Journal of Laryngology & Otology
Published
2026-02-27
DOI
https://doi.org/10.1017/s0022215126104538
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Tumour-infiltrating lymphocytes do not predict survival in human papillomavirus-associated oropharyngeal squamous cell carcinoma: a single institution retrospective review

Robbie Woods, Susan Kennedy, Hannah O'Driscoll, Shane Brennan et al.
The Journal of Laryngology & Otology
Head and Neck Cancer Studies
article

Tumour-infiltrating lymphocytes do not predict survival in human papillomavirus-associated oropharyngeal squamous cell carcinoma: a single institution retrospective review

Robbie Woods, Susan Kennedy, Hannah O'Driscoll, Shane Brennan, Conrad Timon, Michael Fitzsimons, Grace O'Flanagan
article en

Abstract

TIL density in HPV+OPSCC has been reported to predict survival outcomes. This is not supported by the findings of this study. Further prospective evaluation with a standardised scoring technique may fully elicit the prognostic value of TILs in HPV+OPSCC.

The Journal of Laryngology & Otology
Royal College of Surgeons in Ireland (IE), Botsford Hospital (US), Royal Victoria Eye and Ear Hospital (IE), Beaumont Hospital, Dearborn (US), St. James's Hospital (IE)
Openalex Percentile: Top 40%
Head and Neck Cancer Studies
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