Retrospective Comparison of Operational Metrics Across Diagnostic Approaches for Molecular Testing in Lung and Colon Cancers in a Community-Based Setting

SGP provides the fastest TAT but lower detection and higher QNS rates in NSCLC. OFA balances TAT, QNS, and detection, whereas SO-NGS offers comprehensive detection with longer TAT and higher QNS. An optimized assay combining SGP's speed, OFA's reliability, and SO-NGS's comprehensiveness could improve outcomes.

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Publication Details

Journal
Archives of Pathology & Laboratory Medicine
Published
2026-02-26
DOI
https://doi.org/10.5858/arpa.2025-0181-oa
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Retrospective Comparison of Operational Metrics Across Diagnostic Approaches for Molecular Testing in Lung and Colon Cancers in a Community-Based Setting

Jon Thomason, Matthew Aboudara, Russell Smith, Ossama William Tawfik et al.
Archives of Pathology & Laboratory Medicine
Lung Cancer Treatments and Mutations
article

Retrospective Comparison of Operational Metrics Across Diagnostic Approaches for Molecular Testing in Lung and Colon Cancers in a Community-Based Setting

Jon Thomason, Matthew Aboudara, Russell Smith, Ossama William Tawfik, Samuel Caughron
article en

Abstract

SGP provides the fastest TAT but lower detection and higher QNS rates in NSCLC. OFA balances TAT, QNS, and detection, whereas SO-NGS offers comprehensive detection with longer TAT and higher QNS. An optimized assay combining SGP's speed, OFA's reliability, and SO-NGS's comprehensiveness could improve outcomes.

Archives of Pathology & Laboratory Medicine
Saint Luke's Health System (US), Arthritis and Rheumatology Clinics of Kansas (US)
Good health and well-being
Openalex Percentile: Top 41%
Lung Cancer Treatments and Mutations
DOIOpen Access PDFOpenAlex
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