Real-world experience using multiplex polymerase chain reaction in intensive care unit patients with hospital-acquired and ventilator-associated pneumonia in South Korea

mPCR provided faster pathogen identification and earlier antibiotic modifications than conventional respiratory culture. However, antibiotic discontinuation remained uncommon despite negative mPCR results, highlighting challenges in real-world antimicrobial stewardship.

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Publication Details

Journal
Acute and Critical Care
Published
2026-02-27
DOI
https://doi.org/10.4266/acc.005100
Primary Topic
Nosocomial Infections in ICU
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world experience using multiplex polymerase chain reaction in intensive care unit patients with hospital-acquired and ventilator-associated pneumonia in South Korea

Yong Chong, Kyung‐Hyun Do, Jin Won Huh, Su Yeon Lee et al.
Acute and Critical Care
Nosocomial Infections in ICU
article

Real-world experience using multiplex polymerase chain reaction in intensive care unit patients with hospital-acquired and ventilator-associated pneumonia in South Korea

Yong Chong, Kyung‐Hyun Do, Jin Won Huh, Su Yeon Lee, Euijin Chang, Sang-Ho Choi, Eun Chong Yoon, Sang-Bum Hong, Jee Hwan Ahn, Heungsup Sung, Chae-Man Lim, Dong-gon Hyun
article en

Abstract

mPCR provided faster pathogen identification and earlier antibiotic modifications than conventional respiratory culture. However, antibiotic discontinuation remained uncommon despite negative mPCR results, highlighting challenges in real-world antimicrobial stewardship.

Acute and Critical CareVol. 41(1)
Ulsan College (KR), Soonchunhyang University Hospital Seoul (KR), Asan Medical Center (KR), University of Ulsan (KR)
Good health and well-being
Openalex Percentile: Top 43%
Nosocomial Infections in ICU
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