IR-780 improves urination function and complications in rats with partial bladder outlet obstruction by protecting bladder smooth muscle cell mitochondria from oxidative stress
IR-780 improved urinary function and complications in rats with pBOO by protecting BSMC mitochondria from oxidative stress, which was potentially mediated through the activation of the Nrf2 pathway.
Authors
- S Tang
- Feng Pi (ORCID: https://orcid.org/0000-0001-9294-2094)
- Zhihong Huang (ORCID: https://orcid.org/0000-0001-8121-6361)
- Chunmeng Shi
- Benhuang Yan
- Min Jia
- Qiang Fang
- Yuan Liu
- Weibing Li
Institutions
- Southwest General Health Center (US)
- Army Medical University (CN)
- Third People 's Hospital of Chongqing (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fphar.2026.1778496
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00