Bacillus velezensis alleviates PM2.5-induced intestinal injury and dysbiosis in broilers via the “lung-gut axis”
Tracheal instillation of B. velezensis can improve the expression of genes associated with lung injury via the TLR4/MyD88/NF-κB signaling axis and effectively alleviate PM<sub>2.5</sub>-induced distal jejunal damage, barrier dysfunction, inflammatory response, and dysbiosis by mediating the "lung-gut axis". This could provide a theoretical support and scientific basis for seeking probiotics to improve PM<sub>2.5</sub> harm.
Authors
- Christopher Daniel (ORCID: https://orcid.org/0009-0006-6378-8810)
- X.X. Zhang
- Xuan Liu
- Liang Chen
- Dadan Liu
- Hongfu Zhang
Institutions
- Chinese Academy of Agricultural Sciences (CN)
- Feed Research Institute (CN)
- Institute of Animal Sciences (CN)
Publication Details
- Journal
- Animal Microbiome
- Published
- 2026-02-27
- DOI
- https://doi.org/10.1186/s42523-026-00529-w
- Primary Topic
- Animal Nutrition and Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00