Prognostic significance of serum apelin-13 and galectin-3 concentrations as potential indicators of severity and mortality in pediatric acute respiratory distress syndrome

Although the apelin/APJ system's role in acute lung injury is known, its diagnostic and prognostic value in PARDS requires further study. Galectin-3 levels correlate with disease severity and outcomes, highlighting the need for larger, age- and phenotype-homogenized studies to confirm its role as an independent mortality predictor.

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Publication Details

Journal
The Turkish Journal of Pediatrics
Published
2026-02-27
DOI
https://doi.org/10.24953/turkjpediatr.2026.6648
Primary Topic
Galectins and Cancer Biology
Type
article
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article

Prognostic significance of serum apelin-13 and galectin-3 concentrations as potential indicators of severity and mortality in pediatric acute respiratory distress syndrome

Gül Kırtıl, Naz Gülce Koçoğlu, Serçin Taşar, Rukiye Ünsal Saç et al.
The Turkish Journal of Pediatrics
Galectins and Cancer Biology
article

Prognostic significance of serum apelin-13 and galectin-3 concentrations as potential indicators of severity and mortality in pediatric acute respiratory distress syndrome

Gül Kırtıl, Naz Gülce Koçoğlu, Serçin Taşar, Rukiye Ünsal Saç, Ayşe Esra Tapcı, İsmail Bulut, Medine Ayşin Taşar, Nuri Alacakır
article en

Abstract

Although the apelin/APJ system's role in acute lung injury is known, its diagnostic and prognostic value in PARDS requires further study. Galectin-3 levels correlate with disease severity and outcomes, highlighting the need for larger, age- and phenotype-homogenized studies to confirm its role as an independent mortality predictor.

The Turkish Journal of PediatricsVol. 68(1)
Ministry of Health (TR), University of Health Science (KH), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Good health and well-being
Openalex Percentile: Top 40%
Galectins and Cancer Biology
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