The role of clinical laboratory parameters in diabetic neuropathy: correlations and recent advances

Diabetic neuropathy affects approximately 50% of patients with diabetes, causing significant health issues and reducing quality of life. This review examined the associations between diabetic neuropathy and various laboratory parameters, including metabolic indicators, renal and hepatic function parameters, inflammatory biomarkers, thyroid hormones and vitamins. By summarizing the latest evidence on these easily accessible clinical parameters, the article aims to improve risk stratification, enable earlier diagnosis and develop personalized therapeutic strategies, emphasizing the potential of multi-parameter biomarker integration to optimize patient care.