Association between PFAS compounds in follicular fluid and POR and the intervention effect of Qizi Yusi Tang: a study based on targeted PFAS quantification analysis
Patients with Kidney Deficiency-Liver Stagnation Pattern POR exhibited significantly elevated levels of PFAS compounds in follicular fluid compared to IVF controls with normal ovarian reserve. Compared with the control group, patients who received QZYST intervention showed improvements in TCM syndrome manifestations and key clinical outcomes, and significantly lower PFBA levels were observed in the follicular fluid of the TCM intervention group than in those without intervention.
Authors
- Jiacheng Li (ORCID: https://orcid.org/0000-0003-3730-3534)
- Xin Yu Hu
- ZhenGao Sun
- Wenjing Jiang (ORCID: https://orcid.org/0009-0009-9473-1042)
- Hengbing Li
- Jingyan Song
- Zizhen Guo
Institutions
- Tongji University (CN)
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fendo.2026.1758118
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Taishan Scholar Foundation of Shandong Province
- National Key Research and Development Program of China