Proteome-wide Mendelian randomization and colocalization analyses identify potential biomarkers for schizophrenia
This large-scale MR study provides robust evidence supporting causal roles for specific plasma proteins in SCZ pathogenesis, highlighting promising candidates for mechanistic studies and therapeutic development.
Authors
- Yajuan Niu
- Jingxu Chen (ORCID: https://orcid.org/0000-0001-6700-7918)
- Jingyu Lin (ORCID: https://orcid.org/0000-0001-6215-3211)
- Su YA
- L Chen
- Tianmei Si
- Haiming Huang
- Yanyan Wei
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
- Beijing HuiLongGuan Hospital (CN)
- Peking University Sixth Hospital (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fpsyt.2026.1724567
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00