Dysbiosis of intestinal microbiota in patients with neuromyelitis optica spectrum disorders
Our study revealed significant gut microbiome dysbiosis and metabolic abnormalities in patients with NMOSD, which were markedly alleviated after six months of immunosuppressive treatment. These preliminary findings suggest the gut microbiota biomarkers could serve as potential therapeutic targets in the future.
Authors
- H. Zhou (ORCID: https://orcid.org/0000-0003-2060-0436)
- Ziyan Shi
- Lingyao Kong
- Hongxi Chen
- Zichao Mou
- Rui Wang
- Ying Zhang
- Qin Du
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fimmu.2026.1747643
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China