Programmed cell death during plant development

Programmed cell death (PCD) is a fundamental biological process key to development, homeostasis and immune responses in all multicellular life forms. While the molecular regulation of diverse PCD forms have been extensively characterized in animals, the study of PCD in plants has recently gained momentum. Here, we highlight the functional roles of different PCD processes that occur as an integral part of plant development. We discuss the cellular and molecular frameworks governing the initiation and execution of PCD in plants, outline the challenges that have historically impeded progress in the field, and highlight the emerging technological innovations and plant models that are driving current discoveries.