Evolvoid: a genetic algorithm for shaping optimal cellular constructs
Evolvoid is modular, scalable, and tunable to different construct sizes, cell types, or culture conditions, and thus provides a versatile platform for designing and optimizing 3D cellular models entirely in silico. It offers a foundation for developing high-fidelity, cost-effective digital shape twins of biological systems, supporting the advancement of lab-on-a-laptop technologies and new approach methodologies, thereby reducing the reliance on in vitro and animal models.
Authors
- Chiara Magliaro (ORCID: https://orcid.org/0000-0003-2520-4643)
- Ermes Botte (ORCID: https://orcid.org/0000-0001-5058-5316)
- Flavio Fontana
- Arti Ahluwalia
- Francesco Pampaloni
- Piera Mancini
Institutions
- University of Pisa (IT)
- Goethe University Frankfurt (DE)
- Piaggio (Italy) (IT)
- Frankfurt Institute for Advanced Studies (DE)
Publication Details
- Journal
- Journal of Biological Engineering
- Published
- 2026-02-27
- DOI
- https://doi.org/10.1186/s13036-026-00642-z
- Primary Topic
- Topology Optimization in Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00