Multi-omics analysis reveals steroid hormone biosynthesis as a key pathway in advanced maternal age threatened abortion
Disruption of steroid hormone biosynthesis represents central molecular feature to AMA-TA. Integrated multi-omics analysis offers mechanistic insight and supports the development of biomarkers and therapeutic targets for AMA-TA.
Authors
- Aolei Lin (ORCID: https://orcid.org/0000-0002-8793-6199)
- Junjie Deng
- Tianjiao Liu (ORCID: https://orcid.org/0000-0002-8853-9742)
- Xi Liu (ORCID: https://orcid.org/0000-0002-6741-4094)
- Min Xia (ORCID: https://orcid.org/0000-0002-6394-9294)
- Mei Luo
- Xuemei Zou
- Xiaoyan Chen
- Huan Yang
- Zhi Chen
- Cheng Chen
Institutions
- Tianjin Medical University General Hospital (CN)
- Chengdu Women's and Children's Central Hospital (CN)
- Chongqing Three Gorges Central Hospital (CN)
- Chongqing Emergency Medical Center (CN)
- First People's Hospital of Chongqing (CN)
- Chongqing Three Gorges University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Biology of Reproduction
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1093/biolre/ioag045
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00