A CD30-positive variant of intravascular large B-cell lymphoma presenting as diffuse interstitial lung disease and generalized lymphadenopathy: a case report
This case demonstrates that IVLBCL can present with diffuse interstitial lung disease and generalized lymphadenopathy, expanding its recognized phenotypic spectrum. It may represent a variant with CD30-mediated nodal homing and immune activation.
Authors
- Yongdeng Cai
- C Ge
- Lei Wang (ORCID: https://orcid.org/0000-0002-8811-8489)
- Wei Zhang (ORCID: https://orcid.org/0000-0003-0094-3722)
- Zongfang Li
- Yunqing Chen
- Mengyao Wang
- Baomei Mi
- Jianni Zhu
- Zheng Dong
- Yajing Liang
- Lu Wang
- Cui Gao
- Zongtao Liu
- Guangwei Xue
- Cailing Du
Institutions
- Qingdao University (CN)
- People’s Hospital of Rizhao (CN)
- Linyi People's Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fmed.2026.1790176
- Primary Topic
- CNS Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00