Acute post-infusion hypokalemia following rituximab therapy in patients with nephrotic syndrome: case series and literature review

Severe hypokalemia can occur acutely after rituximab infusion in NS, even after prior uneventful exposures. Presentations may be delayed and nonspecific. Clinicians should monitor serum potassium before and after rituximab administration to enable timely recognition and management of this rare complication.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-02-27
DOI
https://doi.org/10.3389/fphar.2026.1770911
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Acute post-infusion hypokalemia following rituximab therapy in patients with nephrotic syndrome: case series and literature review

Lie Jin, Weidong Huang, Y. Xu, Fengfen Wu et al.
Frontiers in Pharmacology
Renal Diseases and Glomerulopathies
article

Acute post-infusion hypokalemia following rituximab therapy in patients with nephrotic syndrome: case series and literature review

Lie Jin, Weidong Huang, Y. Xu, Fengfen Wu, Tingyan Xiang, Lishi Yu, Wenhui Lei
article en

Abstract

Severe hypokalemia can occur acutely after rituximab infusion in NS, even after prior uneventful exposures. Presentations may be delayed and nonspecific. Clinicians should monitor serum potassium before and after rituximab administration to enable timely recognition and management of this rare complication.

Frontiers in PharmacologyVol. 17
Xinjiang Medical University (CN), Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN), Fifth Affiliated Hospital of Xinjiang Medical University (CN), ShenZhen People’s Hospital (CN), Community Health Center (US)
Good health and well-being
Openalex Percentile: Top 48%
Renal Diseases and Glomerulopathies
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