Anxiety is associated with systemic pro-inflammatory profile and plasma lipid changes in Mexican young adults

The data indicate a reproducible pro-inflammatory signal in clinical anxiety and point to modest, exploratory alterations in selected glycerolipids and lysophospholipids that require validation. These results should be considered hypothesis-generating; larger, longitudinal studies are needed to determine causality and the clinical relevance of immunometabolic signatures in anxiety.

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Publication Details

Journal
Frontiers in Cellular Neuroscience
Published
2026-02-27
DOI
https://doi.org/10.3389/fncel.2026.1777048
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Anxiety is associated with systemic pro-inflammatory profile and plasma lipid changes in Mexican young adults

José Alfonso Ontiveros-Sánchez de la Barquera, Alberto Camacho-Morales, Natalia Vázquez-Manjarrez, Rocio Ortiz-Lopez et al.
Frontiers in Cellular Neuroscience
Tryptophan and brain disorders
article

Anxiety is associated with systemic pro-inflammatory profile and plasma lipid changes in Mexican young adults

José Alfonso Ontiveros-Sánchez de la Barquera, Alberto Camacho-Morales, Natalia Vázquez-Manjarrez, Rocio Ortiz-Lopez, Sofía Bernal-Vega, Mariana Villegas-Romero, Antonio Alí Pérez-Maya
article en

Abstract

The data indicate a reproducible pro-inflammatory signal in clinical anxiety and point to modest, exploratory alterations in selected glycerolipids and lysophospholipids that require validation. These results should be considered hypothesis-generating; larger, longitudinal studies are needed to determine causality and the clinical relevance of immunometabolic signatures in anxiety.

Frontiers in Cellular NeuroscienceVol. 20
Universidad Autónoma de Nuevo León (MX), Hospital Universitario Dr José Eleuterio Gonzalez (MX), National Institute of Nutrition (IN), Tecnológico de Monterrey (MX)
Good health and well-being
Openalex Percentile: Top 47%
Tryptophan and brain disorders
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