Impact of biliary fungal contamination on outcomes after pancreaticoduodenectomy for pancreatic cancer

Biliary fungal contamination was not associated with increased risk of postoperative complications in patients with pancreatic cancer but was associated with worse OS, particularly in patients who received neoadjuvant therapy. Investigations regarding the causal relationship between biliary fungus and treatment response and outcome in patients with PDAC are warranted.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-27
DOI
https://doi.org/10.3389/fonc.2026.1776853
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of biliary fungal contamination on outcomes after pancreaticoduodenectomy for pancreatic cancer

J.R. Howe, James P. De Andrade, Hisakazu Hoshi, Scott K. Sherman et al.
Frontiers in Oncology
Pancreatic and Hepatic Oncology Research
article

Impact of biliary fungal contamination on outcomes after pancreaticoduodenectomy for pancreatic cancer

J.R. Howe, James P. De Andrade, Hisakazu Hoshi, Scott K. Sherman, Jeremy Chang, Sophia Xiao, Carlos H. F. Chan, Yutao Su
article en

Abstract

Biliary fungal contamination was not associated with increased risk of postoperative complications in patients with pancreatic cancer but was associated with worse OS, particularly in patients who received neoadjuvant therapy. Investigations regarding the causal relationship between biliary fungus and treatment response and outcome in patients with PDAC are warranted.

Frontiers in OncologyVol. 16
University of Iowa Health Care (US)
Good health and well-being
Openalex Percentile: Top 40%
Pancreatic and Hepatic Oncology Research
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