Impact of COVID-19 vaccination and vaccine type on morbidity and mortality in hospitalized patients: a retrospective cohort study in Egypt

COVID-19 vaccination was associated with improved clinical outcomes, reduced disease severity, and lower mortality among hospitalized patients. Disease severity and comorbidity burden were the strongest predictors of survival. No significant differences were observed among vaccine types in clinical outcomes. These findings support the protective role of COVID-19 vaccination in reducing severe disease and mortality.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-02-27
DOI
https://doi.org/10.3389/fmicb.2026.1792503
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of COVID-19 vaccination and vaccine type on morbidity and mortality in hospitalized patients: a retrospective cohort study in Egypt

Nehal Mohamed Eisa, Haidy M. Sami, Seif El Hadidi, Hayam Ali AlRasheed et al.
Frontiers in Microbiology
SARS-CoV-2 and COVID-19 Research
article

Impact of COVID-19 vaccination and vaccine type on morbidity and mortality in hospitalized patients: a retrospective cohort study in Egypt

Nehal Mohamed Eisa, Haidy M. Sami, Seif El Hadidi, Hayam Ali AlRasheed, Heba Khaled, Mostafa M. Bahaa, Marwa M. Gaballah, Shrouq Sayed Abdelrazik, Heba Salama, Nourhan M. Kamal, Abdelrahman S. H. Refaee, Reem S. Mahmoud, Mostafa Ahmed, Ahmed Essam Abou Warda, Rana A. Hussein, Ramy M. El Sabaa
article en

Abstract

COVID-19 vaccination was associated with improved clinical outcomes, reduced disease severity, and lower mortality among hospitalized patients. Disease severity and comorbidity burden were the strongest predictors of survival. No significant differences were observed among vaccine types in clinical outcomes. These findings support the protective role of COVID-19 vaccination in reducing severe disease and mortality.

Frontiers in MicrobiologyVol. 17
Princess Nourah bint Abdulrahman University (SA), Cairo University (EG), Mansoura University (EG), National University of Pharmacy (UA), Life Care Institute of Medical Sciences & Research (IN), Memorial Foundation (US), Health Affairs (US), Al Azhar University (QA), October 6 University (EG), Menoufia University (EG), Port Said University (EG), Delta University for Science and Technology (EG)
Princess Nourah Bint Abdulrahman University
Good health and well-being
Openalex Percentile: Top 41%
SARS-CoV-2 and COVID-19 Research
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