Diagnostic value of 24-h urinary aldosterone and related biomarkers for screening primary aldosteronism in medication-exposed populations

Under conditions of ongoing antihypertensive medication use, the diagnostic performance of 24h-Uald alone for PA screening is limited. In contrast, UARR, incorporating renin measurements, demonstrates higher diagnostic accuracy and greater clinical utility.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-02-27
DOI
https://doi.org/10.3389/fendo.2026.1792072
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic value of 24-h urinary aldosterone and related biomarkers for screening primary aldosteronism in medication-exposed populations

Ke Chen, S Chen, Hui Yuan, Lin‐Lin Shen et al.
Frontiers in Endocrinology
Hormonal Regulation and Hypertension
article

Diagnostic value of 24-h urinary aldosterone and related biomarkers for screening primary aldosteronism in medication-exposed populations

Ke Chen, S Chen, Hui Yuan, Lin‐Lin Shen, Jiashu Yang, Junyi Wu
article en

Abstract

Under conditions of ongoing antihypertensive medication use, the diagnostic performance of 24h-Uald alone for PA screening is limited. In contrast, UARR, incorporating renin measurements, demonstrates higher diagnostic accuracy and greater clinical utility.

Frontiers in EndocrinologyVol. 17
Beijing Anzhen Hospital (CN)
Good health and well-being
Openalex Percentile: Top 42%
Hormonal Regulation and Hypertension
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