Admixture influences the genetic architecture of DNA methylation in a wild primate hybrid zone

Together, these results demonstrate how admixture can meaningfully alter the genetic architecture of gene regulatory traits in natural hybrid zones. They also suggest that the genetic architecture of DNA methylation is conserved across closely related primates, suggesting that genetic effects on gene regulation may remain stable over timescales that range into the millions of years.

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Publication Details

Journal
Genome biology
Published
2026-02-27
DOI
https://doi.org/10.1186/s13059-026-04013-1
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
0.00
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article

Admixture influences the genetic architecture of DNA methylation in a wild primate hybrid zone

Jordan A. Anderson, Dana Lin, Alberts Sc, Elizabeth A. Archie et al.
Genome biology
Epigenetics and DNA Methylation
article

Admixture influences the genetic architecture of DNA methylation in a wild primate hybrid zone

Jordan A. Anderson, Dana Lin, Alberts Sc, Elizabeth A. Archie, Jenny Tung, Tauras P. Vilgalys
article en

Abstract

Together, these results demonstrate how admixture can meaningfully alter the genetic architecture of gene regulatory traits in natural hybrid zones. They also suggest that the genetic architecture of DNA methylation is conserved across closely related primates, suggesting that genetic effects on gene regulation may remain stable over timescales that range into the millions of years.

Genome biology
University of Notre Dame (US), Canadian Institute for Advanced Research (CA), Leipzig University of Applied Sciences (DE), University of Georgia (US), Duke University (US), Cornell University (US), University of Chicago (US), Evolutionary Genomics (United States) (US), Max Planck Institute for Evolutionary Anthropology (DE), Leipzig University (DE)
Openalex Percentile: Top 40%
Epigenetics and DNA Methylation
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