Systemic inflammation is associated with increased risk of death in population with atherosclerotic cardiovascular disease and chronic kidney disease—a Danish national register study
This study demonstrates that SI is prevalent among patients with ASCVD and CKD being strongly associated with higher risk of mortality and MACE. These findings suggest that SI could serve as a valuable marker to identify patients with ASCVD and CKD who are at particularly high risk and may benefit from targeted preventive interventions.
Authors
- Pierre Johansen (ORCID: https://orcid.org/0000-0002-6287-7508)
- Martin Bødtker Mortensen (ORCID: https://orcid.org/0000-0003-2693-4154)
- Jelena Vukmirica
- Jan Håkon Rudolfsen (ORCID: https://orcid.org/0000-0002-4058-056X)
- Kasper Løwe Lundgren
Institutions
- Johns Hopkins University (US)
- Parthenope University of Naples (IT)
- Novo Nordisk (Denmark) (DK)
- Johns Hopkins Medicine (US)
- Aarhus University Hospital (DK)
- Johns Hopkins University Applied Physics Laboratory (US)
- Johns Hopkins Hospital (US)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fcvm.2026.1749835
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Novo Nordisk