Surgical management of retrosternal thyroid disease: a decennial retrospective analysis

A universally recognized definition of retrosternal thyroid pathology remains elusive. In high-volume centers the cervical approach is sufficient and the rates of thoracic surgical approach is less than 1%. Computed tomography (CT) or magnetic resonance imaging (MRI) of the cervical region are the modalities of choice for investigating the retrosternal component of the thyroid, as they allow accurate assessment of mediastinal extension and facilitate surgical planning. In our study, the integration of the Huins classification and the Cohen & Cho classification proved to be a valid predictive factor for identifying cases that may require a surgical approach beyond the classical Kocher-type cervicotomy. We recommend that retrosternal thyroid pathologies be managed in referral centers equipped with multidisciplinary expertise and adequate surgical experience to ensure optimal outcomes.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-02-27
DOI
https://doi.org/10.3389/fendo.2026.1739552
Primary Topic
Thyroid and Parathyroid Surgery
Type
article
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article

Surgical management of retrosternal thyroid disease: a decennial retrospective analysis

Francesco Quaglino, Giorgia Gavello, Giulia Carbonaro, Marta Breda et al.
Frontiers in Endocrinology
Thyroid and Parathyroid Surgery
article

Surgical management of retrosternal thyroid disease: a decennial retrospective analysis

Francesco Quaglino, Giorgia Gavello, Giulia Carbonaro, Marta Breda, Sara Ruscio, Domenico Galetta, Luca Cestino, Samuela Cannazza
article en

Abstract

A universally recognized definition of retrosternal thyroid pathology remains elusive. In high-volume centers the cervical approach is sufficient and the rates of thoracic surgical approach is less than 1%. Computed tomography (CT) or magnetic resonance imaging (MRI) of the cervical region are the modalities of choice for investigating the retrosternal component of the thyroid, as they allow accurate assessment of mediastinal extension and facilitate surgical planning. In our study, the integration of the Huins classification and the Cohen & Cho classification proved to be a valid predictive factor for identifying cases that may require a surgical approach beyond the classical Kocher-type cervicotomy. We recommend that retrosternal thyroid pathologies be managed in referral centers equipped with multidisciplinary expertise and adequate surgical experience to ensure optimal outcomes.

Frontiers in EndocrinologyVol. 17
Ospedale San Giovanni Bosco (IT), Ospedale Maria Vittoria (IT)
Good health and well-being
Openalex Percentile: Top 42%
Thyroid and Parathyroid Surgery
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