Peripheral Sensory Stimulation for Long-Term Improvement in Mild Cognitive Decline: A Prospective Interventional Study

PISTA stimulation produced sustained improvement in cognition and reduced perceived pain, supporting its promising role as a safe, non-invasive adjunct for neurodegenerative cognitive decline. These findings suggest peripheral sensory activation as a promising driver of functional neuroplasticity and warrant verification in randomized, controlled trials.

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Publication Details

Journal
Brain Sciences
Published
2026-02-27
DOI
https://doi.org/10.3390/brainsci16030265
Primary Topic
Pain Management and Treatment
Type
article
Field-Weighted Citation Impact
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article

Peripheral Sensory Stimulation for Long-Term Improvement in Mild Cognitive Decline: A Prospective Interventional Study

André Stang, George Ayoub, Tom Zhang, Fei Sun
Brain Sciences
Pain Management and Treatment
article

Peripheral Sensory Stimulation for Long-Term Improvement in Mild Cognitive Decline: A Prospective Interventional Study

André Stang, George Ayoub, Tom Zhang, Fei Sun
article en

Abstract

PISTA stimulation produced sustained improvement in cognition and reduced perceived pain, supporting its promising role as a safe, non-invasive adjunct for neurodegenerative cognitive decline. These findings suggest peripheral sensory activation as a promising driver of functional neuroplasticity and warrant verification in randomized, controlled trials.

Brain SciencesVol. 16(3)
Santa Barbara City College (US), Carl von Ossietzky Universität Oldenburg (DE), Bengbu Medical College (CN), Michigan State University (US)
Openalex Percentile: Top 42%
Pain Management and Treatment
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