A longitudinal comparative analysis of serum metabolomic signatures in children with SARS-CoV-2 infection and MIS-C
Pediatric COVID-19 has a characteristic metabolomic signature featuring glucose and aminoacid metabolism, that varies with age and disease phenotype. Our study supports the value of metabolomics to unveil pathways related to host-viral interaction that may also help identify early predictors of disease evolution.
Authors
- E. Bruzzese
- A. Lo Vecchio
- A. Guarino
- J. Troisi
- A. Catzola
- L. Pierri
- M. Poeta
- A. Colucci
- V. Discepolo
- M. Lombardi
Institutions
- University of Salerno (IT)
- Federico II University Hospital (IT)
- University of Naples Federico II (IT)
- European University Institute (IT)
Publication Details
- Journal
- Communications Medicine
- Published
- 2026-02-27
- DOI
- https://doi.org/10.1038/s43856-026-01431-x
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Ministero della Salute