FAM-related prognostic molecular subtype screening identified epithelial-derived MAOA-inhibiting bladder cancer
We developed and validated a novel FAM-related risk signature that effectively predicts prognosis in BLCA. Our findings highlight MAOA as a potential tumor suppressor in bladder cancer, warranting further investigation as a therapeutic target. This FAMR model may facilitate risk stratification and inform personalized treatment strategies for bladder cancer patients.
Authors
- Zeyu Dong
- Xuerui Chen
- Wenyong Yang (ORCID: https://orcid.org/0000-0001-7607-8873)
- Xu He (ORCID: https://orcid.org/0000-0001-7311-7654)
- Liangbin Lin (ORCID: https://orcid.org/0000-0003-0455-2569)
- Huang Yao (ORCID: https://orcid.org/0000-0001-5055-4106)
- Hui Zhuo (ORCID: https://orcid.org/0009-0005-7909-4074)
- Qingqiang Lei (ORCID: https://orcid.org/0009-0003-7482-1688)
- Xu Su
- Miaoyu Zhang
- Taisong Wang
- Hui Yu
- Min Cao
Institutions
- Army Medical University (CN)
- Daping Hospital (CN)
- Third People's Hospital of Chengdu (CN)
- Southwest Jiaotong University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fcell.2026.1732999
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00