Genetic variations in AAK1 and ADAM17 associated with circulatory cytokines changes influence COVID-19 susceptibility and severity

Our findings suggest potential genetic biomarkers in AAK1 and ADAM17 genes that could affect the disease severity and circulating cytokine levels in COVID-19 patients.

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Publication Details

Journal
Human Genomics
Published
2026-02-27
DOI
https://doi.org/10.1186/s40246-026-00928-9
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic variations in AAK1 and ADAM17 associated with circulatory cytokines changes influence COVID-19 susceptibility and severity

Nabil Sulaiman, Amal Bouzid, Maha Saber-Ayad, Q. Hamid et al.
Human Genomics
COVID-19 Clinical Research Studies
article

Genetic variations in AAK1 and ADAM17 associated with circulatory cytokines changes influence COVID-19 susceptibility and severity

Nabil Sulaiman, Amal Bouzid, Maha Saber-Ayad, Q. Hamid, Nour Halabi, Maghazachi AA, Habiba Alsafar, Jalal Taneera, Mohamed Saleh, Thenmozhi Venkatachalam, Leen Eldoahji, Iman M. Talaat, Rifat Hamoudi, Noha M. Elemam
article en

Abstract

Our findings suggest potential genetic biomarkers in AAK1 and ADAM17 genes that could affect the disease severity and circulating cytokine levels in COVID-19 patients.

Human Genomics
Cairo University (EG), Mansoura University (EG), Khalifa University of Science and Technology (AE), McGill University Health Centre (CA), University of Sharjah (AE), Ministry of Interior (IT), Ministry of Health (AE), Institut des Maladies Génétiques Imagine (FR), University College London (GB), Alexandria University (EG)
Zero hunger
Openalex Percentile: Top 41%
COVID-19 Clinical Research Studies
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