Study on brain functional networks and cortical morphological structures in patients with primary insomnia
PI patients show abnormal functional hubs (posterior DMN, CEN parietal lobe), reduced FC (CEN-right cerebellum, posterior DMN-occipital lobe), and cortical morphological changes (left frontoparietal thinning, etc.). These neuroimaging indices are correlated with patients' sleep quality, which can provide a basis for mechanistic research and clinical diagnosis of PI.
Authors
- XiaoPing Cui
- Shangwen Xu
- Hui Li (ORCID: https://orcid.org/0000-0001-9198-3951)
- Xiaoyang Wang (ORCID: https://orcid.org/0000-0002-6347-1235)
- Kaixi Wang (ORCID: https://orcid.org/0009-0002-3697-7051)
- Xiaoyue Jin
- Xiaoling Duan
- Yuning Lin
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Medical University (CN)
- 174th hospital of the People's Liberation Army (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-02-27
- DOI
- https://doi.org/10.3389/fneur.2026.1770086
- Primary Topic
- Sleep and related disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province