A rare twist in the abdomen: diagnostic and therapeutic approaches to omental infarction - a case report and literature review

Intraperitoneal focal fat infarction (IFFI) encompasses a group of rare conditions that are clinically and radiologically similar, arising from focal fatty tissue necrosis. These entities often mimic other acute abdominal conditions such as acute appendicitis or cholecystitis. We present the case of a 65-year-old female with progressive abdominal pain, ultimately diagnosed with IFFI using contrast-enhanced computed tomography (CT). Omental infarction (OI) was the leading diagnosis, though a definitive distinction from epiploic appendagitis (EA) could not be made on imaging. Conservative management with anti-inflammatory medication, analgesia, and low-molecular-weight heparins (LMWH) proved effective, resulting in complete resolution within five days. This case highlights the diagnostic value of CT-imaging in differentiating IFFI from other causes of acute abdomen, thereby avoiding unnecessary surgical interventions. The aetiology of OI will be discussed, along with a detailed focus on management strategies that may also apply to other causes of IFFI.

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Publication Details

Journal
Acta Gastro Enterologica Belgica
Published
2026-03-02
DOI
https://doi.org/10.51821/89.1.14216
Primary Topic
Omental and Epiploic Conditions
Type
article
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article

A rare twist in the abdomen: diagnostic and therapeutic approaches to omental infarction - a case report and literature review

Mathieu Lefere, E Ruts, P Bossuyt
Acta Gastro Enterologica Belgica
Omental and Epiploic Conditions
article

A rare twist in the abdomen: diagnostic and therapeutic approaches to omental infarction - a case report and literature review

Mathieu Lefere, E Ruts, P Bossuyt
article en

Abstract

Intraperitoneal focal fat infarction (IFFI) encompasses a group of rare conditions that are clinically and radiologically similar, arising from focal fatty tissue necrosis. These entities often mimic other acute abdominal conditions such as acute appendicitis or cholecystitis. We present the case of a 65-year-old female with progressive abdominal pain, ultimately diagnosed with IFFI using contrast-enhanced computed tomography (CT). Omental infarction (OI) was the leading diagnosis, though a definitive distinction from epiploic appendagitis (EA) could not be made on imaging. Conservative management with anti-inflammatory medication, analgesia, and low-molecular-weight heparins (LMWH) proved effective, resulting in complete resolution within five days. This case highlights the diagnostic value of CT-imaging in differentiating IFFI from other causes of acute abdomen, thereby avoiding unnecessary surgical interventions. The aetiology of OI will be discussed, along with a detailed focus on management strategies that may also apply to other causes of IFFI.

Acta Gastro Enterologica BelgicaVol. 89(1)
University of Antwerp (BE), Imelda Hospital (BE)
Good health and well-being
Openalex Percentile: Top 43%
Omental and Epiploic Conditions
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