Association between initial norepinephrine dose and minute by minute mean arterial pressure

Higher initial NE doses were associated with both larger and faster MAP increases. Lower starting doses appeared insufficient to achieve a target MAP within 60 min in patients with severe hypotension.

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Publication Details

Journal
Critical Care
Published
2026-02-26
DOI
https://doi.org/10.1186/s13054-026-05920-2
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between initial norepinephrine dose and minute by minute mean arterial pressure

Takahiro Kinoshita, Nobuaki Shime, Shinichiro Ohshimo, Kiyono Nobayashi et al.
Critical Care
Sepsis Diagnosis and Treatment
article

Association between initial norepinephrine dose and minute by minute mean arterial pressure

Takahiro Kinoshita, Nobuaki Shime, Shinichiro Ohshimo, Kiyono Nobayashi, Mitsuaki Nishikimi
article en

Abstract

Higher initial NE doses were associated with both larger and faster MAP increases. Lower starting doses appeared insufficient to achieve a target MAP within 60 min in patients with severe hypotension.

Critical Care
Hiroshima University (JP), Aichi Medical University (JP), Medication Management (United States) (US)
Good health and well-being
Openalex Percentile: Top 42%
Sepsis Diagnosis and Treatment
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