Retigabine ameliorates CRS-induced depressive-like behaviors and cognitive impairment by inhibiting endoplasmic reticulum stress-mediated apoptosis

Retigabine may alleviate CRS-induced depressive-like behaviors and cognitive impairment by inhibiting ERS-mediated apoptosis, suggesting its potential as a novel therapeutic strategy for depression.

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Publication Details

Journal
Brain Research Bulletin
Published
2026-02-26
DOI
https://doi.org/10.1016/j.brainresbull.2026.111798
Primary Topic
Endoplasmic Reticulum Stress and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Retigabine ameliorates CRS-induced depressive-like behaviors and cognitive impairment by inhibiting endoplasmic reticulum stress-mediated apoptosis

Jinjing Zhang, Yi-Heng Li, Shuai-Bing Chen, Jin-Qiong Zhan et al.
Brain Research Bulletin
Endoplasmic Reticulum Stress and Disease
article

Retigabine ameliorates CRS-induced depressive-like behaviors and cognitive impairment by inhibiting endoplasmic reticulum stress-mediated apoptosis

Jinjing Zhang, Yi-Heng Li, Shuai-Bing Chen, Jin-Qiong Zhan, Bo Wei, Jian Hu, Jing Zhang
article en

Abstract

Retigabine may alleviate CRS-induced depressive-like behaviors and cognitive impairment by inhibiting ERS-mediated apoptosis, suggesting its potential as a novel therapeutic strategy for depression.

Brain Research BulletinVol. 237
Harbin Medical University (CN), Jiangxi Mental Health Center (CN), First Affiliated Hospital of Harbin Medical University (CN)
Openalex Percentile: Top 41%
Endoplasmic Reticulum Stress and Disease
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