Neonatal steroid exposure and body composition in preterm infants at discharge

Corticosteroids are regularly utilized in neonatal intensive care units, and the impact of these medications on body composition in preterm neonates is unclear. Our study found no significant difference in fat mass (FM), %FM, or fat-free mass (FFM) z-scores between very preterm (VPT) infants with and without steroid exposure. Our study highlights the feasibility of using bioelectrical impedance analysis (BIA) to assess body composition in the NICU.

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Publication Details

Journal
Pediatric Research
Published
2026-02-27
DOI
https://doi.org/10.1038/s41390-026-04796-w
Primary Topic
Neonatal Respiratory Health Research
Type
article
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Neonatal steroid exposure and body composition in preterm infants at discharge

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Neonatal Respiratory Health Research
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Neonatal steroid exposure and body composition in preterm infants at discharge

Leah Cerwinske, Katherine Bell, Jieun David, Kousiki Patra, Tricia J. Johnson, Megan Kraemer, Delaney Mulcahy, Quyen M. Diep, Aloka L. Patel, Bradley M. Appelhans
article en

Abstract

Corticosteroids are regularly utilized in neonatal intensive care units, and the impact of these medications on body composition in preterm neonates is unclear. Our study found no significant difference in fat mass (FM), %FM, or fat-free mass (FFM) z-scores between very preterm (VPT) infants with and without steroid exposure. Our study highlights the feasibility of using bioelectrical impedance analysis (BIA) to assess body composition in the NICU.

Pediatric Research
Brigham and Women's Hospital (US), Rush University Medical Center (US), Food and Nutrition Service (US), Rush University (US)
Zero hunger
Openalex Percentile: Top 42%
Neonatal Respiratory Health Research
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