Graded extent of hippocampal resection is related to neuropsychological outcomes in temporal lobe epilepsy surgery

These findings highlight the critical role of the left hippocampus in supporting both verbal and visual memory and underscore the importance of preserving hippocampal tissue during left ATL when feasible. Our results support the utility of AEC-guided tailored resections as a strategy to balance seizure control with cognitive preservation.

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Publication Details

Journal
Epilepsia
Published
2026-02-26
DOI
https://doi.org/10.1002/epi.70162
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Graded extent of hippocampal resection is related to neuropsychological outcomes in temporal lobe epilepsy surgery

Arka N. Mallela, Luke Henry, Danielle Carns, E. Robinson et al.
Epilepsia
Epilepsy research and treatment
article

Graded extent of hippocampal resection is related to neuropsychological outcomes in temporal lobe epilepsy surgery

Arka N. Mallela, Luke Henry, Danielle Carns, E. Robinson, Bradford Z. Mahon, Catherine LiéGeois-Chauvel, Eliza Reedy, Jorge A Gonzalez-Martinez, Natalie Sherry, Thandar Aung
article en

Abstract

These findings highlight the critical role of the left hippocampus in supporting both verbal and visual memory and underscore the importance of preserving hippocampal tissue during left ATL when feasible. Our results support the utility of AEC-guided tailored resections as a strategy to balance seizure control with cognitive preservation.

Epilepsia
Rush University Medical Center (US), Cornell University (US), University of Pittsburgh Medical Center (US), Neurological Surgery (US), Carnegie Mellon University (US)
Openalex Percentile: Top 47%
Epilepsy research and treatment
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