Extracellular Adenosine Contributes to the Hydrogen Peroxide-Induced Calcification of Cultured Tendon Cells
The enhanced osteogenic calcification of the tendon cell culture by hydrogen peroxide was associated with an increase in extracellular nucleotide metabolites, especially adenosine, with some evidence of causality.
Authors
- Akira Nifuji (ORCID: https://orcid.org/0000-0002-8182-4380)
- Yoichi Ezura (ORCID: https://orcid.org/0000-0001-6310-4526)
- Xin Lin (ORCID: https://orcid.org/0000-0002-8294-3154)
- Hiroyuki Yoshitake
- Masaki Noda
- Tomomi Sakuma
- Chantida P. N. Mahasarakham
Institutions
- Tsurumi University (JP)
- Tokyo Medical and Dental University (JP)
- Teikyo Heisei University (JP)
- Khon Kaen University (TH)
- Institute for Stem Cell Biology and Regenerative Medicine (IN)
- Japan Sport Council (JP)
- Iketani Science and Technology Foundation (JP)
Publication Details
- Journal
- Current Issues in Molecular Biology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3390/cimb48030244
- Primary Topic
- Heterotopic Ossification and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00