A combined immune–nutritional score as a prognostic indicator in neoadjuvant-treated esophageal squamous cell carcinoma
The GRIm-CONUT composite score is an independent predictor of pCR, OS, and RFS in ESCC patients undergoing neoadjuvant therapy and surgery. As an inexpensive and readily obtainable biomarker, it enables more accurate prognostic stratification and may support personalized perioperative management. Prospective multicenter validation is warranted.
Authors
- Zhiqiang Yang (ORCID: https://orcid.org/0000-0002-8951-9401)
- Xiaolin Ye (ORCID: https://orcid.org/0000-0003-0086-0601)
- Xiayu Fu (ORCID: https://orcid.org/0000-0001-6181-2916)
- C. Huang
- C. Chen
- Junpeng Zhan
- Yong Zhu
- Qichang Xie
- Bin Zheng
Institutions
- Fujian Medical University (CN)
- Zhangzhou Municipal Hospital of Fujian Province (CN)
- 175th Hospital of People's Liberation Army (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3389/fimmu.2026.1764277
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China