Pathogen and Patient Characteristics and the Severity of Viral Respiratory Infections in Children
In this cohort study of hospitalized children, respiratory syncytial virus and influenza infections, as well as the presence of chronic comorbidities, were significantly associated with severe disease. These findings support the need for targeted prevention and vaccination strategies, as well as early identification of children at risk for severe disease. The INF-ACT network offered a scalable model for real-time infectious disease monitoring in pediatric populations.
Authors
- L Galli
- Agnese Tamborino (ORCID: https://orcid.org/0009-0009-2278-1120)
- Claudio Cafagno (ORCID: https://orcid.org/0000-0003-3951-1679)
- Cristina Moracas
- C. Colomba
- Valeria Garbo
- Marta Stracuzzi (ORCID: https://orcid.org/0000-0003-2899-3190)
- Ester Del Tufo
- Alfredo Guarino (ORCID: https://orcid.org/0000-0003-0199-0336)
- Andrea Lo Vecchio (ORCID: https://orcid.org/0000-0003-4181-6842)
- Vania Giacomet (ORCID: https://orcid.org/0000-0002-0217-160X)
- Sofia Sgubbi
- Laura Petrarca
- Marco Poeta
- Marco Maglione
- Gian Luigi Marseglia
Institutions
- University of Pavia (IT)
- Federico II University Hospital (IT)
- Santobono Children's Hospital (IT)
- Ospedale Pediatrico Giovanni XXIII (IT)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- ASST Fatebenefratelli Sacco (IT)
- University of Florence (IT)
- University of Naples Federico II (IT)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-02-26
- DOI
- https://doi.org/10.1001/jamanetworkopen.2026.0129
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 0.00